Washington.- Scientists of Harvard University and the Massachusetts Institute of Technology assure that once taken these pills go down to the stomach and dissolve there.
The senior author of the study, Giovanni Traverso, explained that humidity dissolves the plain part of the pill (formed by a sugar) and uncovers a microscopic needle which digs in and discharges its content in the stomach wall, as it were a sting.
The gastroenterologist says the developed device is capable of self-orienting itself in miliseconds, assuring that the end of the injection makes immediate contact with the tissue.
Each capsule is the size of a pea and is charged with a needle containing between 0.3 and 0.5 mm of insulin combined with polyethylene oxide.
The rest of the materials (stainless steel and biodegradable polymers) is similar to those of other devices already approved by the Food and Drug Administration of the United States, asserted the specialists.
They also reported that after swallowing it and having shed its content, it can be excreted with no harm for the digestive system.
The fact it acts inside the stomach makes it spread faster in the organism than a normal subcutaneous injection, although in order to work the patient must be on an empty stomach, they warn.
This technology is the most powerful described to this day, for the oral administration of proteins has been a challenge on which the scientific community has been working on for the last century, assured María José Alonso, of the University of Santiago de Compostela, in Spain.
For the time, it has only been tested in animals as laboratory rats and pigs, but the results have been satisfactory. (PL)
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